Adenosine deamination is catalyzed by an enzyme called adenosine deaminase acting on RNA (ADAR), and results in the formation of inosine in a process called A-to-I RNA editing. RNA editing plays a crucial role in RNA metabolism, splicing, nuclear export and localization. Inosine 5'-triphosphate (ITP) also functions as an alternative substrate for ATPases and GTPases and has been used to study activation and binding kinetics of nucleoside interaction with various ATPases and GTPases.
Product Details
Catalog No
N-1020
Purity
≥98% by AX-HPLC
Extinction Coefficient
12,300 Lmol-1cm-1 at 248 nm
Molecular Formula
C10H15N4O14P3 (free acid)
Molecular Weight
508.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Recommended Storage
-20°C or below
Other Name(s)
ITP, Hypoxanthine
Application
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
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