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Oligo Modifications
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Type
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5' Terminal Caps (Capped Oligos)
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5' Guanosine-triphosphate Cap
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5' Guanosine-triphosphate Cap
5' Guanosine-triphosphate Cap - (O-0274)
Product Details
OLIGObuilder Code |
{Gppp.} |
Other Name(s) |
5' Gppp |
Design Requirements |
5′ guanosine triphosphate oligos are not compatible with free amine modifications. |
Oligo Modification Type |
5' Terminal Caps (Capped Oligos) |
References
Konarska, M. M.; Padgett, R. A.; Sharp, P. A. . Recognition of cap structure in splicing in vitro of mRNA precursors.
Lim, Siew Pheng; Sonntag, Louis Sebastian; Noble, Christian; Nilar, Shahul H.; Ng, Ru Hui; Zou, Gang; Monaghan, Paul; Chung, Ka Yan; Dong, Hongping; Liu, Boping; Bodenreider, Christophe; Lee, Gladys; Ding, Mei; Chan, Wai Ling; Wang, Gang; Jian, Yap Li; Chao, Alexander Theodore; Lescar, Julien; Yin, Zheng; Vedananda, T. R.; Keller, Thomas H.; Shi, Pei-Yong . Small molecule inhibitors that selectively block dengue virus methyltransferase.
Shatkin, A. J. . Capping of eucaryotic mRNAs.
Furuichi, Y.; LaFiandra, A.; Shatkin, A. J. . 5'-Terminal structure and mRNA stability.
Edery, I.; Sonenberg, N. . Cap-dependent RNA splicing in a HeLa nuclear extract.
Kozak, M. . Structural features in eukaryotic mRNAs that modulate the initiation of translation.
Murthy, K. G.; Park, P.; Manley, J. L. . A nuclear micrococcal-sensitive, ATP-dependent exoribonuclease degrades uncapped but not capped RNA substrates.
Izaurralde, E.; Stepinski, J.; Darzynkiewicz, E.; Mattaj, I. W. . A cap binding protein that may mediate nuclear export of RNA polymerase
Hatta, T.; Ishikawa, M.; Takai, K.; Nakada, S.; Yokota, T.; Hata, T.; Miura, K.; Takaku, H. . Inhibition of influenza virus RNA polymerase by 5'-capped short RNA fragments.
Tado, M.; Abe, T.; Hatta, T.; Ishikawa, M.; Nakada, S.; Yokota, T.; Takaku, H. . Inhibitory effect of modified 5'-capped short RNA fragments on influenza virus RNA polymerase gene expression.
Egloff, Marie-Pierre; Benarroch, Delphine; Selisko, Barbara; Romette, Jean-Louis; Canard, Bruno . An RNA cap (nucleoside-2'-O-)-methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization.
Hooker, Lisa; Sully, Rachel; Handa, Balraj; Ono, Naomi; Koyano, Hiroshi; Klumpp, Klaus . Quantitative analysis of influenza virus RNP interaction with RNA cap structures and comparison to human cap binding protein eIF4E.
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