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CpG RNA Dinucleotide (5'-3') - (O-31007)

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This product is now available upon request as a custom synthesis. It is not maintained as a stocked item.

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Description

5 OD260 (0.278 µmoles) 25 OD260 (1.39 µmoles) 100 OD260 (5.56µmoles) 

Product Details

Catalog No O-31007
Purity ≥95% by AX-HPLC
Extinction Coefficient 18,000 Lmol-1cm-1 at 260 nm
Molecular Formula C19H25N8O12P (free acid)
Molecular Weight 588.40 g/mole (free acid)
Salt Form Na+
Concentration -
Recommended Storage -20°C or below
Application In vitro Transcription
Backbone Phosphodiester
Base Analog(s) Cytidine, Guanosine
Nucleotide Category 5'-3' Dinucleotide

Supporting Documents

O-31007 Safety Data Sheet

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Certificate of Analysis

CoA Search Tool

Intellectual Property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.

TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.

References

Honda, A.; Mizumoto, K.; Ishihama, A. . RNA polymerase of influenza virus. Dinucleotide-primed initiation of transcription at specific positions on viral RNA.

Samuels, M.; Fire, A.; Sharp, P. A. . Dinucleotide priming of transcription mediated by RNA polymerase II.

Krieg, A. M.; Yi, A. K.; Matson, S.; Waldschmidt, T. J.; Bishop, G. A.; Teasdale, R.; Koretzky, G. A.; Klinman, D. M. . CpG motifs in bacterial DNA trigger direct B-cell activation.

Stevanin, Mathias; Busso, Nathalie; Chobaz, Véronique; Pigni, Matteo; Ghassem-Zadeh, Sahar; Zhang, Li; Acha-Orbea, Hans; Ehirchiou, Driss . CD11b regulates the Treg/Th17 balance in murine arthritis via IL-6.

Durham, Nick M.; Holoweckyj, Nick; MacGill, Randall S.; McGlinchey, Kelly; Leow, Ching Ching; Robbins, Scott H. . GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory.

Voss, James E.; Macauley, Matthew S.; Rogers, Kenneth A.; Villinger, Francois; Duan, Lijie; Shang, Liang; Fink, Elizabeth A.; Andrabi, Raiees; Colantonio, Arnaud D.; Robinson, James E.; Johnson, R. Paul; Burton, Dennis R.; Haase, Ashley T. . Reproducing SIVΔnef vaccine correlates of protection: trimeric gp41 antibody concentrated at mucosal front lines.

Chen, Sam; Zaifman, Josh; Kulkarni, Jayesh A.; Zhigaltsev, Igor V.; Tam, Ying K.; Ciufolini, Marco A.; Tam, Yuen Yi C.; Cullis, Pieter R. . Dexamethasone prodrugs as potent suppressors of the immunostimulatory effects of lipid nanoparticle formulations of nucleic acids.

Baptista, AP;Gola, A;Huang, Y;Milanez-Almeida, P;Torabi-Parizi, P;Urban, JF;Shapiro, VS;Gerner, MY;Germain, RN; . The Chemoattractant Receptor Ebi2 Drives Intranodal Naive CD4+ T Cell Peripheralization to Promote Effective Adaptive Immunity

Lilic, M;Darst, SA;Campbell, EA; . Structural basis of transcriptional activation by the Mycobacterium tuberculosis intrinsic antibiotic-resistance transcription factor WhiB7

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