1. Home
  2. Oligo Modifications
  3. Type
  4. 5' Terminal Caps (Capped Oligos)
  5. 5' Adenylate
  6. 5' Adenylate

5' Adenylate - (O-0264)

rApp, 5' Adenylation
main product photo
-->

This modification is available as part of a custom oligonucleotide configuration. Please use OLIGObuilder™ to generate pricing and order or contact us to speak with a customer service representative.

Ready to order your oligonucleotide?

Build My Oligo

Product Details

OLIGObuilder Code {rApp.}
Other Name(s) rApp, 5' Adenylation
Design Requirements To prevent a 5′ adenylated oligo from self-ligating, a blocking group is required on the 3′-end, such as a 2′,3′-Dideoxynucleotide or 3’ (C3) Propyl Spacer.5′ adenylated oligos require an extra purification after the adenylation step and are not compatible with heat-sensitive modifications.
Oligo Modification Type 5' Terminal Caps (Capped Oligos)

Product FAQs

Ask an Expert

References

Lau, N. C.; Lim, L. P.; Weinstein, E. G.; Bartel, D. P. . An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans.

Zhuang, Fanglei; Fuchs, Ryan T.; Sun, Zhiyi; Zheng, Yu; Robb, G. Brett . Structural bias in T4 RNA ligase-mediated 3'-adapter ligation.

Sriskanda, Verl; Shuman, Stewart . Role of nucleotidyltransferase motifs I, III and IV in the catalysis of phosphodiester bond formation by Chlorella virus DNA ligase.

Related Posts

""