7-Deazaguanosine-5'-Triphosphate is a guanosine triphosphate analog which lacks a nitrogen at the N7 position of the nucleobase. Replacement of this nitrogen atom with a carbon atom results in diminished structure of the major groove in DNA and may disrupt base stacking, but does not interfere with Watson-Crick base pairing. This is desirable for applications such as amplification and sequencing of GC-rich nucleic acid sequences.
Product Details
Catalog No
N-1044
Purity
≥90% by AX-HPLC
Extinction Coefficient
9,145 Lmol-1cm-1 at 259 nm
Molecular Formula
C11H17N4O14P3 (free acid)
Molecular Weight
522.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2O
Recommended Storage
-20°C or below
Other Name(s)
7-Deaza-GTP
Application
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.
TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.
