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7-Deaza-2'-deoxyadenosine-5'-Triphosphate - (N-2010)

7-Deaza-dATP
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Product Details

Catalog No N-2010
Purity ≥90% by AX-HPLC
Extinction Coefficient 9,500 Lmol-1cm-1 at 271 nm
Molecular Formula C11H17N4O12P3 (free acid)
Molecular Weight 490.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 7-Deaza-dATP
Application Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone 5'-Triphosphate
Base Analog(s) Adenosine
Sugar Type(s) DNA
Nucleotide Category Base Modified DNA

Supporting Documents

N-2010 Safety Data Sheet

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Certificate of Analysis

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Intellectual Property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.

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2'-Deoxynucleoside-5'-Triphosphate Set - (N-2505)

References

Wood, David O.; Dinsmore, Michael J.; Bare, Grant A.; Lee, Jeremy S. . M-DNA is stabilised in G*C tracts or by incorporation of 5-fluorouracil.

Devadoss, Babho; Lee, Irene; Berdis, Anthony J. . Enhancing the "A-rule" of translesion DNA synthesis: promutagenic DNA synthesis using modified nucleoside triphosphates.

Pivoňková, Hana; Horáková, Petra; Fojtová, Miloslava; Fojta, Miroslav . Direct Voltammetric Analysis of DNA Modified with Enzymatically Incorporated 7-Deazapurines

Zhang, Xuemei; Motea, Edward; Lee, Irene; Berdis, Anthony J. . Replication of a Universal Nucleobase Provides Unique Insight into the Role of Entropy during DNA Polymerization and Pyrophosphorolysis

Patro, Jennifer N.; Urban, Milan; Kuchta, Robert D. . Interaction of Human DNA Polymerase and DNA Polymerase I fromBacillus stearothermophiluswith Hypoxanthine and 8-Oxoguanine Nucleotides

Zhang, Yinbo; Baranovskiy, Andrey G.; Tahirov, Emin T.; Tahirov, Tahir H.; Pavlov, Youri I. . Divalent ions attenuate DNA synthesis by human DNA polymerase α by changing the structure of the template/primer or by perturbing the polymerase reaction.

Gowda, A. S. Prakasha; Krzeminski, Jacek; Amin, Shantu; Suo, Zucai; Spratt, Thomas E. . Mutagenic Replication of N(2)-Deoxyguanosine Benzo[a]pyrene Adducts by Escherichia coli DNA Polymerase I and Sulfolobus solfataricus DNA Polymerase IV.

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