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Catalog Products
Nucleoside Triphosphates & Nucleotides
Base Modified NTPs
5-Methyluridine-5'-Triphosphate
5-Methyluridine-5'-Triphosphate
5-Methyluridine-5'-Triphosphate - (N-1024)
5-Methyl-UTP, 5-Me-UTP, 5-mUTP
Product Details
Catalog No
N-1024
Purity
≥90% by AX-HPLC
Extinction Coefficient
9,650 Lmol-1 cm-1 at 267 nm
Molecular Formula
C10 H17 N2 O15 P3 (free acid)
Molecular Weight
498.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2 O
Recommended Storage
-20°C or below
Other Name(s)
5-Methyl-UTP, 5-Me-UTP, 5-mUTP
Application
Aptamers, Epigenetics/DNA Damage, In vitro Transcription, Mutagenesis, Photocrosslinking Studies
Backbone
5'-Triphosphate
Base Analog(s)
Thymidine, Uridine
Sugar Type(s)
RNA
Nucleotide Category
Base Modified RNA
Intellectual Property
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.
TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.
References
Karikó, Katalin; Muramatsu, Hiromi; Welsh, Frank A.; Ludwig, János; Kato, Hiroki; Akira, Shizuo; Weissman, Drew . Incorporation of pseudouridine into mRNA yields superior nonimmunogenic vector with increased translational capacity and biological stability.
Karikó, Katalin; Buckstein, Michael; Ni, Houping; Weissman, Drew . Suppression of RNA recognition by Toll-like receptors: the impact of nucleoside modification and the evolutionary origin of RNA.
Anderson, Bart R.; Muramatsu, Hiromi; Nallagatla, Subba R.; Bevilacqua, Philip C.; Sansing, Lauren H.; Weissman, Drew; Karikó, Katalin . Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation.
Schein, Catherine H.; Oezguen, Numan; van der Heden van Noort, Gerbrand J.; Filippov, Dmitri V.; Paul, Aniko; Kumar, Eric; Braun, Werner . NMR solution structure of poliovirus uridylyated peptide linked to the genome (VPgpU).
Motorin, Yuri; Helm, Mark . RNA nucleotide methylation.
Lai, Zijuan; Tsugawa, Hiroshi; Wohlgemuth, Gert; Mehta, Sajjan; Mueller, Matthew; Zheng, Yuxuan; Ogiwara, Atsushi; Meissen, John; Showalter, Megan; Takeuchi, Kohei; Kind, Tobias; Beal, Peter; Arita, Masanori; Fiehn, Oliver . Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics.
Randrianjatovo-Gbalou, Irina; Rosario, Sandrine; Sismeiro, Odile; Varet, Hugo; Legendre, Rachel; Coppée, Jean-Yves; Huteau, Valérie; Pochet, Sylvie; Delarue, Marc . Enzymatic synthesis of random sequences of RNA and RNA analogues by DNA polymerase theta mutants for the generation of aptamer libraries.
Potapov, Vladimir; Fu, Xiaoqing; Dai, Nan; Corrêa, Ivan R. Jr; Tanner, Nathan A.; Ong, Jennifer L. . Base modifications affecting RNA polymerase and reverse transcriptase fidelity.
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