5'-Biotin-G-Monophosphate - (N-6003)


This product is now available upon request as a custom synthesis. It is not maintained as a stocked item.


5'-Biotin-G-Monophosphate allows for the incorporation of biotin at the 5' terminus of RNA. This reagent is especially useful for the development of aptamers.

Product Details

Catalog No N-6003
Purity ≥95% by AX-HPLC
Extinction Coefficient 13,700 Lmol-1cm-1 at 253 nm
Molecular Formula C26H41N8O10PS (free acid)
Molecular Weight 688.70 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 5'-Biotin-GMP
Backbone 5'-Biotin-Monophosphate
Base Analog(s) Guanosine
Sugar Type(s) RNA
Nucleotide Category Biotin Labeled

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Kim, Yun-Hee; Sung, Ho Jin; Kim, Sukyoung; Kim, Eun-Ok; Lee, Ji Won; Moon, Ju Young; Choi, Kyungho; Jung, Ji-Eun; Lee, Yangsoon; Koh, Sang Seok; Rhee, Sue Goo; Heo, Kyun; Kim, In-Hoo . An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells.

Bompiani, K. M.; Monroe, D. M.; Church, F. C.; Sullenger, B. A. . A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.

Collett, James R.; Cho, Eun Jeong; Ellington, Andrew D. . Production and processing of aptamer microarrays.

Pratico, Elizabeth D.; Sullenger, Bruce A.; Nair, Smita K. . Identification and characterization of an agonistic aptamer against the T cell costimulatory receptor, OX40.

Bandyra, Katarzyna J.; Sinha, Dhriti; Syrjanen, Johanna; Luisi, Ben F.; De Lay, Nicholas R. . The ribonuclease polynucleotide phosphorylase can interact with small regulatory RNAs in both protective and degradative modes.

Iaboni, Margherita; Fontanella, Raffaela; Rienzo, Anna; Capuozzo, Maria; Nuzzo, Silvia; Santamaria, Gianluca; Catuogno, Silvia; Condorelli, Gerolama; de Franciscis, Vittorio; Esposito, Carla Lucia . Targeting Insulin Receptor with a Novel Internalizing Aptamer.

Gefen, Tal; Castro, Iris; Muharemagic, Darija; Puplampu-Dove, Yvonne; Patel, Shradha; Gilboa, Eli . A TIM-3 Oligonucleotide Aptamer Enhances T Cell Functions and Potentiates Tumor Immunity in Mice.

Suddala, Krishna C.; Cabello-Villegas, Javier; Michnicka, Malgorzata; Marshall, Collin; Nikonowicz, Edward P.; Walter, Nils G. . Hierarchical mechanism of amino acid sensing by the T-box riboswitch.

Huang, CC;Ray, P;Chan, M;Zhou, X;Hall, DA; . An aptamer-based magnetic flow cytometer using matched filtering

Gray, BP;Requena, MD;Nichols, MD;Sullenger, BA; . Aptamers as Reversible Sorting Ligands for Preparation of Cells in Their Native State

Huang, CC; . Magnetoresistive Devices for Biosensing Applications