5'-Biotin-G-Monophosphate - (N-6003)

5'-Biotin-GMP

This product is now available upon request as a custom synthesis. It is not maintained as a stocked item.

Description

5'-Biotin-G-Monophosphate allows for the incorporation of biotin at the 5' terminus of RNA. This reagent is especially useful for the development of aptamers.

Product Details

Catalog No N-6003
Purity ≥95% by AX-HPLC
Extinction Coefficient 13,700 Lmol-1cm-1 at 253 nm
Molecular Formula C26H41N8O10PS (free acid)
Molecular Weight 688.70 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) 5'-Biotin-GMP
Backbone 5'-Biotin-Monophosphate
Base Analog(s) Guanosine
Sugar Type(s) RNA
Nucleotide Category Biotin Labeled

Supporting Documents


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Certificate of Analysis


Intellectual Property

Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.

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References

Kim, Yun-Hee; Sung, Ho Jin; Kim, Sukyoung; Kim, Eun-Ok; Lee, Ji Won; Moon, Ju Young; Choi, Kyungho; Jung, Ji-Eun; Lee, Yangsoon; Koh, Sang Seok; Rhee, Sue Goo; Heo, Kyun; Kim, In-Hoo . An RNA aptamer that specifically binds pancreatic adenocarcinoma up-regulated factor inhibits migration and growth of pancreatic cancer cells.

Bompiani, K. M.; Monroe, D. M.; Church, F. C.; Sullenger, B. A. . A high affinity, antidote-controllable prothrombin and thrombin-binding RNA aptamer inhibits thrombin generation and thrombin activity.

Collett, James R.; Cho, Eun Jeong; Ellington, Andrew D. . Production and processing of aptamer microarrays.

Pratico, Elizabeth D.; Sullenger, Bruce A.; Nair, Smita K. . Identification and characterization of an agonistic aptamer against the T cell costimulatory receptor, OX40.

Bandyra, Katarzyna J.; Sinha, Dhriti; Syrjanen, Johanna; Luisi, Ben F.; De Lay, Nicholas R. . The ribonuclease polynucleotide phosphorylase can interact with small regulatory RNAs in both protective and degradative modes.

Iaboni, Margherita; Fontanella, Raffaela; Rienzo, Anna; Capuozzo, Maria; Nuzzo, Silvia; Santamaria, Gianluca; Catuogno, Silvia; Condorelli, Gerolama; de Franciscis, Vittorio; Esposito, Carla Lucia . Targeting Insulin Receptor with a Novel Internalizing Aptamer.

Gefen, Tal; Castro, Iris; Muharemagic, Darija; Puplampu-Dove, Yvonne; Patel, Shradha; Gilboa, Eli . A TIM-3 Oligonucleotide Aptamer Enhances T Cell Functions and Potentiates Tumor Immunity in Mice.

Suddala, Krishna C.; Cabello-Villegas, Javier; Michnicka, Malgorzata; Marshall, Collin; Nikonowicz, Edward P.; Walter, Nils G. . Hierarchical mechanism of amino acid sensing by the T-box riboswitch.

Huang, CC;Ray, P;Chan, M;Zhou, X;Hall, DA; . An aptamer-based magnetic flow cytometer using matched filtering

Gray, BP;Requena, MD;Nichols, MD;Sullenger, BA; . Aptamers as Reversible Sorting Ligands for Preparation of Cells in Their Native State

Huang, CC; . Magnetoresistive Devices for Biosensing Applications



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