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Catalog Products
Nucleoside Triphosphates & Nucleotides
Sugar Modified NTPs
3'-Deoxyadenosine-5'-Triphosphate
3'-Deoxyadenosine-5'-Triphosphate
3'-Deoxyadenosine-5'-Triphosphate - (N-3001)
Description
3'-Deoxyadenosine-5'-Triphosphate lacks a hydroxyl group at the 3' position of the ribose sugar, which prevents elongation of the RNA past the site of incorporation. In the case of mRNA this results in expression of a truncated protein.
Product Details
Catalog No
N-3001
Purity
≥90% by AX-HPLC
Extinction Coefficient
15,400 Lmol-1 cm-1 at 258 nm
Molecular Formula
C10 H16 N5 O12 P3 (free acid)
Molecular Weight
491.10 g/mole (free acid)
Salt Form
Li+
Concentration
100 mM
Buffer
H2 O
Recommended Storage
-20°C or below
Other Name(s)
3'-dATP
Application
Aptamers
Backbone
5'-Triphosphate
Base Analog(s)
Adenosine
Sugar Type(s)
3'-Deoxy
Nucleotide Category
Sugar Modified
Intellectual Property
Products are for research use only, not for use in diagnostic or therapeutic procedures or for use in humans. Products are not for resale without express written permission of Seller. No license under any patent or other intellectual property right of Seller or its licensors is granted or implied by the purchase unless otherwise provided in writing.
TriLink does not warrant that the use or sale of the products delivered hereunder will not infringe the claims of any United States or other patents or patents pending covering the use of the product alone or in combination with other products or in the operation of any process. All and any use of TriLink product is the purchaser's sole responsibility.
References
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Corigliano, Eleonora M.; Perona, John J. . Architectural Underpinnings of the Genetic Code for Glutamineâ€Â
Yakhnin, Alexander V.; Babitzke, Paul . NusA-stimulated RNA polymerase pausing and termination participates in the Bacillus subtilis trp operon attenuation mechanism invitro.
Latour, Derek R.; Jekle, Andreas; Javanbakht, Hassan; Henningsen, Robert; Gee, Peter; Lee, Ina; Tran, Patricia; Ren, Suping; Kutach, Alan K.; Harris, Seth F.; Wang, Sandra M.; Lok, Stephen J.; Shaw, David; Li, Jim; Heilek, Gabrielle; Klumpp, Klaus; Swinney, David C.; Deval, Jerome . Biochemical characterization of the inhibition of the dengue virus RNA polymerase by beta-d-2'-ethynyl-7-deaza-adenosine triphosphate.
Niyomrattanakit, Pornwaratt; Abas, Siti Nurdiana; Lim, Chin Chin; Beer, David; Shi, Pei-Yong; Chen, Yen-Liang . A fluorescence-based alkaline phosphatase-coupled polymerase assay for identification of inhibitors of dengue virus RNA-dependent RNA polymerase.
Maida, Yoshiko; Yasukawa, Mami; Masutomi, Kenkichi . De Novo RNA Synthesis by RNA-Dependent RNA Polymerase Activity of Telomerase Reverse Transcriptase.
Lu, Gaofei; Bluemling, Gregory R.; Collop, Paul; Hager, Michael; Kuiper, Damien; Gurale, Bharat P.; Painter, George R.; De La Rosa, Abel; Kolykhalov, Alexander A. . Analysis of Ribonucleotide 5'-Triphosphate Analogs as Potential Inhibitors of Zika Virus RNA-Dependent RNA Polymerase by Using Nonradioactive Polymerase Assays.
Uemura, K;Nobori, H;Sato, A;Sanaki, T;Toba, S;Sasaki, M;Murai, A;Saito-Tarashima, N;Minakawa, N;Orba, Y;Kariwa, H;Hall, WW;Sawa, H;Matsuda, A;Maenaka, K; . 5-Hydroxymethyltubercidin exhibits potent antiviral activity against flaviviruses and coronaviruses, including SARS-CoV-2
Piscotta, FJ;Hoffmann, HH;Choi, YJ;Small, GI;Ashbrook, AW;Koirala, B;Campbell, EA;Darst, SA;Rice, CM;Brady, SF; . Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals
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