2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate) - (N-8011)

Alpha Thiol ddGTP, 1-Thio-ddGTP
SKU Unit Size Price Qty
N-8011-1 1 µmole
N-8011-5 5 µmole
N-8011-10 10 µmole


2',3'-Dideoxyguanosine-5'-O-(1-Thiotriphosphate) is a sugar modified nucleoside triphosphate where the 2' and 3' hydroxyl groups are absent, resulting in chain termination. This ddGTP analog also contains a 1-Thiotriphosphate which results in a nuclease resistant phosphorothioate linkage. The inability of polymerases to extend from a dideoxy nucleotide causes chain termination and is useful in antiviral research and in a variety of biotechnology applications.

Product Details

Catalog No N-8011
Purity ≥90% by AX-HPLC
Extinction Coefficient 13,600 Lmol-1cm-1 at 252 nm
Molecular Formula C10H16N5O11P3S (free acid)
Molecular Weight 507.20 g/mole (free acid)
Salt Form Li+
Concentration 100 mM
Buffer H2O
Recommended Storage -20°C or below
Other Name(s) Alpha Thiol ddGTP, 1-Thio-ddGTP
Backbone 5'-O-(1-Thiotriphosphate)
Base Analog(s) Guanosine
Sugar Type(s) 2'-3'-Dideoxy
Nucleotide Category Phosphate Modified

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